With the continuous expansion of the world economy, trade, and personnel exchanges, the problem of transnational crime is gradually spreading on a global scale. As one of the countries with significant influence in Asia, Thailand has significant geographical and strategic advantages in Southeast Asia. With deeper cooperation between China and Thailand in various fields such as economy, society, and culture, transnational crime between the two countries has also increased. Therefore, it is of great necessity and practical significance for China and Thailand to deepen police cooperation, jointly combat transnational crime, and maintain social security and stability within their respective countries and regions This article attempts to focus on the law enforcement cooperation between China and Thailand, explore the internal mechanisms of the two countries in the process of cooperating to combat cross-border crimes, analyze the main problems that exist, and further explore the favorable and unfavorable factors that affect the cooperation between the two countries in law enforcement, striving to find corresponding countermeasures and suggestions, and effectively ensure the smooth development of China Thailand law enforcement cooperation.